This error can bring any repair attempt to a screeching halt. It signals that the software cannot read the firmware package (usually an OZIP or OFP file) you are trying to flash.
This is the most common cause. Your download was interrupted, leaving the central directory incomplete.
If the official Realme Flash Tool refuses to cooperate, ditch it entirely. Use generic Qualcomm tools.
Windows User Account Control (UAC) and antivirus software can intercept the tool’s attempt to read the central directory.