"Project Hail Mary" takes place in a not-too-distant future where Earth is on the brink of extinction. A catastrophic event, known as the "Great Filter," has caused a significant decrease in the number of habitable planets in the galaxy, threatening the very survival of humanity. In a last-ditch effort to ensure the continuation of their species, a team of scientists and engineers embark on a top-secret mission to find a new habitable planet.

The story follows Ryland Grace, a former astronaut who wakes up on a spaceship called the "Hail Mary," with no memory of who he is or how he got there. As he tries to piece together his past, he discovers that he is on a mission to travel to a distant star system in search of a planet capable of supporting human life. The ship is equipped with a cutting-edge AI system, an "autodoc" that can repair and maintain the vessel, and a mysterious payload known as the "astrophage."

For readers interested in accessing "Project Hail Mary" in EPUB format, there are several options available. Many e-book retailers, including Amazon and Barnes & Noble, offer the novel in EPUB format. Additionally, some online libraries and book lending services provide access to EPUB copies of the book.